Can diet affect eczema flare-ups?
The Journal 4 min read

Can diet affect eczema flare-ups?

Yes, diet can significantly influence eczema flare-ups, though the relationship is complex and highly individualised. While atopic dermatitis is primarily a genetic skin barrier defect, systemic inflammation driven by dietary intake can exacerbate symptoms. In many patients, particularly children, true IgE-mediated food allergies can trigger immediate skin reactions. Common culprits include cow's milk, eggs, soy, and wheat, which may provoke an inflammatory cascade that worsens pruritus and erythema [1]. 

Beyond clinical allergies, certain dietary patterns may influence the skin's inflammatory threshold. High intake of ultra-processed foods, high-glycemic index carbohydrates, and saturated fats has been associated with increased systemic inflammation, potentially lowering the barrier for an eczema flare-up to occur [2]. Conversely, diets rich in omega-3 fatty acids and antioxidants may provide a protective effect by modulating the immune response and supporting the lipid barrier of the stratum corneum [3]. However, it is essential to distinguish between a food allergy and a food sensitivity, as unnecessary elimination diets can lead to nutritional deficiencies without necessarily clearing the skin [1].

The 'gut-skin axis' is the primary scientific framework used to understand how diet influences eczema. This bidirectional communication pathway suggests that the composition of the gut microbiome plays a crucial role in immune system regulation. Dysbiosis, or an imbalance in gut bacteria, can lead to increased intestinal permeability—often colloquially termed 'leaky gut'—which allows pro-inflammatory mediators to enter the systemic circulation and manifest as skin inflammation [4]. 

From a biochemical perspective, specific nutrients act as co-factors for skin barrier repair. For instance, linoleic acid is critical for the synthesis of ceramides, the 'mortar' between skin cells. If a diet is deficient in essential fatty acids or contains an excess of pro-inflammatory omega-6 relative to omega-3, the structural integrity of the skin barrier may be compromised, making it more susceptible to environmental irritants and allergens [5].

While managing dietary triggers is a vital internal step, supporting the skin’s external ecosystem is equally important for maintaining a balanced complexion. For those navigating the complexities of a compromised barrier, our Balance Biome Crème is formulated with Bifida Ferment Lysate to support microbiome resilience, while Surface Calm provides a gentle, ceramide-rich cleansing experience that respects the skin’s natural defence layers.

 

 

FAQ

Should everyone with eczema go on a gluten-free diet?

Current evidence does not support a gluten-free diet for all eczema sufferers. While there is a higher prevalence of celiac disease markers in patients with atopic dermatitis, gluten only triggers flares in those with a specific sensitivity or allergy to it. Routine elimination without a clinical diagnosis may not improve skin outcomes and can lead to unnecessary dietary restriction [6].

Can probiotics help reduce eczema symptoms?

Clinical trials have shown mixed results, but there is promising evidence that specific strains, such as Lactobacillus rhamnosus, may help prevent eczema development in infants when taken by the mother during pregnancy or by the child in early infancy [4]. For adults, probiotics may help modulate the immune response, but they are generally viewed as a complementary therapy rather than a primary treatment [7].

Are sugar and dairy the biggest triggers for skin inflammation?

Dairy is one of the most common triggers, especially in paediatric cases, due to its allergenic potential. High-sugar diets can increase insulin-like growth factor 1 (IGF-1), which may promote inflammation. However, while some patients see dramatic improvements upon removing these, others see no change, highlighting the need for personalised dietary assessment [2][8].

 

 

References:
[1] Werfel T, et al. Position paper on diagnosis and treatment of food allergy in atopic dermatitis. Allergy. 2007;62(7):723-728. doi:10.1111/j.1398-9995.2007.01426.x
[2] Katta R, Schlichte M. Diet and dermatitis: food triggers. J Clin Aesthet Dermatol. 2014;7(3):30-36.
[3] Miles EA, Calder PC. Omega-6 and omega-3 fatty acids and inflammation. Microorganisms. 2021;9(6):1241. doi:10.3390/microorganisms9061241
[4] Salem I, et al. The Gut Microbiome as a Major Regulator of the Gut-Skin Axis. Front Microbiol. 2018;9:1459. doi:10.3389/fmicb.2018.01459
[5] Schlichte MJ, et al. Diet and eczema: a review of dietary supplements for the treatment of atopic dermatitis. Dermatol Pract Concept. 2016;6(3):23-29. doi:10.5826/dpc.0603a06
[6] Nosrati A, et al. Dietary modifications in atopic dermatitis: patient-reported outcomes. J Dermatolog Treat. 2017;28(6):523-538. doi:10.1080/09546634.2016.1278071
[7] Rather IA, et al. The Microbiome and Atopic Dermatitis: More Than Skin Deep. Nutrients. 2016;8(5):260. doi:10.3390/nu8050260
[8] Finch J, et al. Atopic dermatitis and nutrition. Clin Dermatol. 2010;28(6):605-614. doi:10.1016/j.clindermatol.2010.03.032

Medical Disclaimer: This article is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any new skincare regimen. Content reviewed by a biomedical scientist.

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